Product Name: APY0201
Chemical Name: (E)-4-(5-(2-(3-methylbenzylidene)hydrazinyl)-2-(pyridin-4-yl)pyrazolo[1,5-a]pyrimidin-7-yl)morpholine
SMILES Code: CC1=CC(/C=N/NC2=NC3=CC(C4=CC=NC=C4)=NN3C(N5CCOCC5)=C2)=CC=C1
CAS NO: 484-29-7 Product: NSC 405020
Synonym: APY-0201
Chemical Formula: C23H23N7O
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Immunology_Inflammation inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: APY0201 is a potent and selective IL-12/23 inhibitor. APY0201 demonstrates ameliorated inflammation in an experimental model of colitis. Interleukin-12 (IL-12) and IL-23 are proinflammatory cytokines and therapeutic targets for inflammatory and autoimmunePubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22469131