Product Name: AGI-6780
Chemical Name: N-cyclopropyl-4-(thiophen-3-yl)-3-(3-(3-(trifluoromethyl)phenyl)ureido)benzenesulfonamide
SMILES Code: O=S(C1=CC=C(C2=CSC=C2)C(NC(NC3=CC=CC(C(F)(F)F)=C3)=O)=C1)(NC4CC4)=O
CAS NO: 148-82-3 Product: 5S rRNA modificator
Synonym: AGI 6780; AGI6780
Chemical Formula: C21H18F3N3O3S2
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).NF-κB inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: AGI-6780 is a potent and selective IDH2 inhibitor, which inhibits the tumor-associated mutant IDH2/R140Q. Treatment with AGI-6780 induced differentiation of TF-1 erythroleukemia and primary human acute myelogenous leukemia cells in vitro. Inhibitors targePubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19359544
