Product Name: AG-221
Chemical Name: 2-methyl-1-((4-(6-(trifluoromethyl)pyridin-2-yl)-6-((2-(trifluoromethyl)pyridin-4-yl)amino)-1,3,5-triazin-2-yl)amino)propan-2-ol
SMILES Code: CC(O)(C)CNC1=NC(C2=NC(C(F)(F)F)=CC=C2)=NC(NC3=CC(C(F)(F)F)=NC=C3)=N1
CAS NO: 1133432-46-8 Product: GSK2141795 (hydrochloride)
Synonym: Enasidenib, AG 221; AG221; CC-90007; CC 90007; CC90007
Chemical Formula: C19H17F6N7O
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).BMX Kinase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: AG-221 (Enasidenib, CC-90007) is a potent and selective IDH2 inhibitor with potential anticancer activity. The mutations of IDH2 present in certain cancer cells result in a new ability of the enzyme to catalyze the NAPH-dependent reduction of α-ketoglutarPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/10465261
