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Product Name: A-1210477
Chemical Name: 7-(5-((4-(4-(N,N-dimethylsulfamoyl)piperazin-1-yl)phenoxy)methyl)-1,3-dimethyl-1H-pyrazol-4-yl)-1-(2-morpholinoethyl)-3-(3-(naphthalen-1-yloxy)propyl)-1H-indole-2-carboxylic acid
SMILES Code: O=C(C(N1CCN2CCOCC2)=C(CCCOC3=C(C=CC=C4)C4=CC=C3)C5=C1C(C6=C(COC7=CC=C(N8CCN(S(=O)(N(C)C)=O)CC8)C=C7)N(C)N=C6C)=CC=C5)O
CAS NO: 176161-24-3 Product: Ramosetron (Hydrochloride)
Synonym: A 1210477; A1210477
Chemical Formula: C46H55N7O7SMolecular Weight: 850.05
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Ribosomal S6 Kinase RSK) inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: A-1210477 is a potent and selective MCL-1 inhibitor, which induces the hallmarks of intrinsic apoptosis and demonstrates single agent killing of multiple myeloma and non-small cell lung cancer cell lines. A-1210477 synergizes with the BCL-2/BCL-XL inhibitPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/6111196

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Author: DNA_ Alkylatingdna