Product Name: YO-01027 (Dibenzazepine) | gamma-secretase inhibitor
Product Description: YO-01027 (Dibenzazepine, DBZ) is a dipeptidic g-secretase inhibitor with IC50 of 2.6 and 2.9 nM for APPL and Notch, respectively. YO-01027 targets the Presenilin fragment. Increasing concentrations of YO-01027 administered to APPl- or Notch-expressing celWeb Site：Medchemexpress
Chemical Formula: C26H23F2N3O3
Molecular Weight: 463.48
‘&“CAS NO: 0 XMU-MP-1
Purity: 98%
Appearance: White
Chemical Name: 7-(S)-[N(3,5-difluorophenylacetyl)-L-alaninyl]amino-5-methyl-5,7-dihydro-6H-dibenz[b,d]azepin-6-oneFXR inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24747911
