Product Name: VX-770 (Ivacaftor) | CFTR potentiator
Product Description: VX-770 (Ivacaftor) is a CFTR potentiator and has been shown to potentiate normal CFTR, as well as CFTR with G551D and F508-del mutations. Ivacaftor directly binds to the ion channel, causes conformation change and open the ion channel to improve chloride Medchemexpress
Chemical Formula: C24H28N2O3
Molecular Weight: 392.49
‘&“CAS NO: 204005-46-9 SU5416
Purity: 98%
Appearance: Off-white
Chemical Name: N-(2,4-di-tert-butyl-5-hydroxyphenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamidenAChR inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder or DMSO solution at -20oC desiccated.PubMed ID:http://onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2012.01974.x/abstract
