Product Name: VX-765 | Caspase 1/Interleukin-converting enzyme inhibitor
Product Description: VX-765 is an orally-available prodrug of VRT-043198, an inhibitor of interleukin-converting enzyme / caspase-1 subfamily caspases. VRT-043198 shows Ki values of 0.8 nM and 100-fold selectivity over other non-ICE subfamily caspases. VRT-043198 showed no siMedchemexpress.com
Chemical Formula: C24H33ClN4O6
Molecular Weight: 509
‘&“CAS NO: 22033-87-0 TRO 19622
Purity: 98%
Appearance: white
Chemical Name: (S)-1-((S)-2-(4-amino-3-chlorobenzamido)-3,3-dimethylbutanoyl)-N-((2R,3S)-2-ethoxy-5-oxotetrahydrofuran-3-yl)pyrrolidine-2-carboxamideFAAH inhibitors
Solubility: Up to 50 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22440753
