Product Name: VX-702 | P38 MAPK inhibitor
Product Description: VX-702 is an orally-available, aminopyridine-based, ATP-competitive inhibitor of p38 MAPK with a Kd of 3.7 nM and 17 nM at 10 uM for p38a and p38b, respectively. [1] In an ex vivo blood assay primed with LPS< VX-702 dose-dependently inhibited the produMedchemexpress.com
Chemical Formula: C19H12F4N4O2
Molecular Weight: 404.32
‘&“CAS NO: 1044870-39-4 RVX-208
Purity: 98%
Appearance: White
Chemical Name: 1-(5-carbamoyl-6-(2,4-difluorophenyl)pyridin-2-yl)-1-(2,6-difluorophenyl)ureaSRPK inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pmc/articles/PMC86555/
