Product Name: Sorafenib | Raf1 inhibitor
Product Description: Sorafenib (BAY 43-9006) is biarylurea-based inhibitor of Raf1 (IC50, 6 nM) with additional activity against B-Raf, mVEGFR2, mPDGFRb (IC50, 22 nM, 15 nM, and 57 nM respectively), and related kinases. [1] In MDA-MB-231 breast cancer cells, sorafenib efficieWeb Site click
Chemical Formula: C21H16ClF3N4O3
Molecular Weight: 464.82
‘&“CAS NO: 1562338-42-4 LMI070
Purity: 99%
Appearance: White
Chemical Name: 4-(4-(3-(4-chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N-methylpicolinamideDNA Stain inhibitors
Solubility: Up to 100mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25680461
