Product Name: Skepinone-L | p38 MAPK inhibitor
Product Description: Skepinone-L is an ATP-competitive, dibenzosuberone-based inhibitor of p38-MAPK and TNF-a, with IC50 values of 5 and 40 nM, respectively. [1] At 1000 nM, Skepinone-L (Kd = 1.5 nM) did not inhibit any other member of an Ambit panel of 402 kinases. [2]In vitWeb Site：Medchemexpress
Chemical Formula: C24H21F2NO4
Molecular Weight: 425.42
‘&“CAS NO: 1693758-51-8 IPI549
Purity: 99%
Appearance: Yellow
Chemical Name: (R)-2-((2,4-difluorophenyl)amino)-7-(2,3-dihydroxypropoxy)-10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-onePPAR inhibitors
Solubility: Up to 22 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://jpet.aspetjournals.org/content/317/2/571.abstract
