Product Name: SB203580 | p38 MAPK inhibitor
Product Description: SB203580 is a pyridinylimidazole-based inhibitor of p38-MAPK at an IC50 of 0.3-0.5 uM. [1] It also inhibits PKB phosphorylation at an IC50 of 3-5 uM and blocks the key cell cycle event of retinoblastoma protein phosphorylation in IL-2-stimulated T-cells. Medchemexpress.com
Chemical Formula: C21H16FN3OS
Molecular Weight: 377.43
‘&“CAS NO: 0 GNE-617 (hydrochloride)
Purity: 98%
Appearance: White
Chemical Name: 4-(4-(4-fluorophenyl)-2-(4-(methylsulfinyl)phenyl)-1H-imidazol-5-yl)pyridineSurvivin inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16354677?dopt=Abstract
