Product Name: PP242 | mTOR inhibitor
Product Description: PP242 is an ATP-competitive, pyrazolopyrimidine-based inhibitor of mTOR at an IC50 of 8 nM. It is highly selective against the PI3K family of kinases, with all but one isoform (p110g IC50 = 102 nM) registering with IC50s > 1 uM. In a broad kinase panelWeb Site:Medchemexpress
Chemical Formula: C16H16N6O
Molecular Weight: 308.34
‘&“CAS NO: 1231930-82-7 LY2835219
Purity: 98%
Appearance: Greyish Purple
Chemical Name: 2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-yl)-1H-indol-5-olIAP inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16335928