Product Name: PLX-4032 (Vemurafenib) | B-Raf inhibitor
Product Description: PLX4032 (Vemurafenib) is an 7-azaindole-based, orally-available, inhibitor of the B-Raf V600E mutation with an IC50 of 30 nM. [1] In preclinical tumor models, PLX4032 induces antiproliferative effects in both mealonama and thyroid cell lines, with a simulMedchemexpress
Chemical Formula: C23H18ClF2N3O3S
Molecular Weight: 489.92
‘&“CAS NO: 1229705-06-9 RG7388
Purity: 98%
Appearance: White
Chemical Name: N-(3-(5-(4-chlorophenyl)-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonamideCheckpoint Kinase (Chk) inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.pnas.org/content/108/39/16375.full
