Product Name: PHA-665752 | cMET/RON inhibitor
Product Description: PHA-665752 is an oxindole-based, ATP-competitive c-Met and Ron inhibitor with IC50 potencies of 9 nM, and 68 nM, respectively. [1] It is >50-fold selective compared to a broad panel of both tyrosine and serine-threonine kinases. In cellular studies, PHWeb Site:Medchemexpress
Chemical Formula: C32H34Cl2N4O4S
Molecular Weight: 641.61
‘&“CAS NO: 1190308-01-0 PSI-7976
Purity: 98%
Appearance: Yellow
Chemical Name: (R,Z)-5-(2,6-dichlorobenzylsulfonyl)-3-((3,5-dimethyl-4-(2-(pyrrolidin-1-ylmethyl)pyrrolidine-1-carbonyl)-1H-pyrrol-2-yl)methylene)indolin-2-oneMEK inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/15769863