Product Name: PF-04217903 | cMet inhibitor
Product Description: PF-04217903 is a triazolopyrazine-based, ATP-competitive inhibitor of c-Met with Ki and cellular IC50 potency of 4 nM and 5 nM, respectively. [1] In a broad panell of over 200 kinases, PF-04217903 showed >1000-fold selectivity for c-Met. For c-Met mutaWeb Site click
Chemical Formula: C20H20N8O4S
Molecular Weight: 468.49
‘&“CAS NO: 944396-07-0 NVP-BKM120
Purity: 98%
Appearance: White
Chemical Name: 2-(4-(3-(quinolin-6-ylmethyl)-3H-[1,2,3]triazolo[4,5-b]pyrazin-5-yl)-1H-pyrazol-1-yl)ethanol mesylateJNK inhibitors
Solubility: Up to 15 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://clincancerres.aacrjournals.org/content/13/10/3087