Product Name: LY2886721 | BACE inhibitor
Product Description: LY2886721 is an orally-available, furothiazine-based inhibitor of b-amyloid protein cleaving enzyme (BACE) for the treatment of Alzheimers disease. [1] It inhibits recombinant hBACE1 with an IC50 of 20 nM. [2] In cellular assays, LY2886721 inhibits AbetaMedchemexpress
Chemical Formula: C18H16F2N4O2S
Molecular Weight: 390.41
‘&“CAS NO: 1229208-44-9 GS-9973
Purity: 98%
Appearance: White
Chemical Name: N-(3-((4aS,7aS)-2-amino-4a,5,7,7a-tetrahydro-4H-furo[3,4-d][1,3]thiazin-7a-yl)-4-fluorophenyl)-5-fluoropicolinamideAdenosine Kinase inhibitors
Solubility: Up to 20 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16595737
