Product Name: JNJ-28431754 (Canagliflozin) | SGLT2 inhibitor
Product Description: Canagliflozin is an orally-available, C-aryl glucoside inhibitor of hSGLT2, rSGLT2, and mSGLT2 cells at a potency of 4.4, 3.7, and 2.0 nM, respectively. [1] It inhibits AMG uptake in CHO-hSGLT1 cells with an IC50 of 684 nM. Canagliflozin lowers renal glucWeb Site click
Chemical Formula: C24H25FO5S
Molecular Weight: 444.52
‘&“CAS NO: 175013-84-0 Tonabersat
Purity: 98%
Appearance: White
Chemical Name: (2S,3R,4R,5S,6R)-2-(3-((5-(4-fluorophenyl)thiophen-2-yl)methyl)-4-methylphenyl)-6-(hydroxymethyl)-tetrahydro-2H-pyran-3,4,5-triolAnti-infection inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18687985
