Product Name: GDC-0449 (Vismodegib) | Hedgehog pathway inhibitor
Product Description: GDC-0449 (Vismodegib) is a potent, orally bioavailable, specific hedgehog pathway small-molecule inhibitor with IC50 of 3 nM. It blocks the activities of the Hedgehog-ligand cell surface receptor SMO and suppresses Hedgehog signaling [1].The hedgehog (HH)Medchemexpress
Chemical Formula: C19H14Cl2N2O3S
Molecular Weight: 421.3
‘&“CAS NO: 6809-52-5 Teprenone
Purity: 98%
Appearance: White
Chemical Name: 2-chloro-N-(4-chloro-3-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamideTAK1 inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://pubs.acs.org/doi/abs/10.1021/ml200261d
