Product Name: GDC-0068 | Pan-Akt inhibitor
Product Description: GDC-0068 is a potent, highly selective, orally available, ATP-competitive pan-AKT inhibitor, targeting Akt1, Akt2 and Akt3 with IC50 of 5 nM, 18 nM and 8 nM, respectively. It demonstrates high selectivityover more than 200 screened kinases, with >100 fMedchemexpress
Chemical Formula: C24H32ClN5O2
Molecular Weight: 458
‘&“CAS NO: 1616391-65-1 EPZ015666
Purity: 98%
Appearance: White
Chemical Name: (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-oneApoptosis inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/27347692