Product Name: BX-912 | PDK1 inhibitor
Product Description: BX-912 is an aminopyrimidine-based, ATP-competitive inhibitor of PDK1 at an IC50 of 12 nM. In a panel of relevant serine-threonine and receptor-tyrosine kinases, BX-912 showed at least 20-fold selectivity with the exception of 9-fold selectivity (110 nM) Web Site：Medchemexpress
Chemical Formula: C20H23BrN8O
Molecular Weight: 471.35
‘&“CAS NO: 169869-90-3 Exatecan (Mesylate)
Purity: 98%
Appearance: white
Chemical Name: N-(3-(4-(2-(1H-imidazol-5-yl)ethylamino)-5-bromopyrimidin-2-ylamino)phenyl)pyrrolidine-1-carboxamideADC Linker inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://jpet.aspetjournals.org/content/327/1/268
