Product Name: BMS-708163 (Avagacestat) | γ-secretase inhibitor
Product Description: BMS-708163 (Avagacestat) is a potent and selective inhibitor for gamma-secretase, especially at inhibiting cleavage of amyloid precursor protein (APP) to form amyloid-ß (Aß)(1-40) (IC50=0.3nM) and Aß(1-42) (0.27nM). BMS-708163 is Notch Web Site click
Chemical Formula: C20H17ClF4N4O4S
Molecular Weight: 520.88
‘&“CAS NO: 379231-04-6 Saracatinib
Purity: 98%
Appearance: White
Chemical Name: (2R)-2-(N-(2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl)-4-chlorophenylsulfonamido)-5,5,5-trifluoropentanamide15-PGDH inhibitors
Solubility: Up to 50 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17577318
