Product Name: BIRB796 (Doramapimod) | P38 MAPK inhibitor
Product Description: BIRB796 (Doramapimod) is a pyrazole-based allosteric inhibitor of p38 MAP Kinase with a Kd of 0.1 nM. BIRB796 has slow binding kinetics, as evidenced by an marked increase in apparent IC50 after preincubation periods up to 2h, as well as dissociation rateMedchemexpress.com
Chemical Formula: C31H37N5O3
Molecular Weight: 527.66
‘&“CAS NO: 1257044-40-8 ABT-199
Purity: 98%
Appearance: White
Chemical Name: 1-(3-tert-butyl-1-p-tolyl-1H-pyrazol-5-yl)-3-(4-(2-morpholinoethoxy)naphthalen-1-yl)urea – See more at: http://www.selleckchem.com/products/BIRB-796-(Doramapimod).html#sthash.FpSrDH3J.dpufHDAC inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25150091
