Product Name: AZD6244 (Selumetinib) | MEK1 inhibitor
Product Description: AZD-6244 (Selumetinib) is an orally-available, aminobenzimidazole-based, allosteric inhibitor of MEK1 kinase with an IC50 of 14 nM. [1] IC50 concentrations of <40 nM were observed in cellular phosphorylation assays measuring ERK1/2 in various cell linMedchemexpress
Chemical Formula: C17H15BrClFN4O3
Molecular Weight: 457.68
‘&“CAS NO: 1643913-93-2 PAK4-IN-1
Purity: 98%
Appearance: White
Chemical Name: 6-(4-bromo-2-chlorophenylamino)-7-fluoro-N-(2-hydroxyethoxy)-3-methyl-3H-benzo[d]imidazole-5-carboxamideG-quadruplex inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17554144
