Product Name: AZ-628 | Raf inhibitor
Product Description: AZ628 is a quinazolinone-based pan-Raf kinase inhibitor with IC50 values of 105, 34, and 29 nM for b-Raf, bRafV600E, and c-Raf-1, respectively. [1] It is selective over a wide panel of RTKs, including VEGFR2, DDR2, Lyn, Flt1, and FMS. AZ628 inhibits anchoMedchemexpress
Chemical Formula: C27H25N5O2
Molecular Weight: 451.52
‘&“CAS NO: 23007-85-4 MPTP (hydrochloride)
Purity: 99%
Appearance: White
Chemical Name: 3-(2-cyanopropan-2-yl)-N-(4-methyl-3-(3-methyl-4-oxo-3,4-dihydroquinazolin-6-ylamino)phenyl)benzamideULK inhibitors
Solubility: Up to 22 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.nature.com/nature/journal/v450/n7170/full/nature06261.html