Product Name: AP24534 (Ponatinib) | Abl, Src, FGFR, VEGFR inhibitor
Product Description: Ponatinib (AP24534) is a imidazopyridine-based pan-inhibitor of the kinases Abl, Abl(T315I), and other clinically important Abl kinase domain mutants at potencies of 0.37 nM, 2.0 nM, and 0.30-0.44 nM, respectively. Ponatinib also potently inhibits Src, VEWeb Site：Medchemexpress
Chemical Formula: C29H27F3N6O
Molecular Weight: 532.57
‘&“CAS NO: 156161-89-6 BQ-788 (sodium salt)
Purity: 98%
Appearance: White
Chemical Name: 3-(2-(imidazo[1,2-b]pyridazin-3-yl)ethynyl)-4-methyl-N-(4-((4-methylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)benzamideDNA Methyltransferase inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/9048762
