Product Name: AMG-706 (Motesanib) | Pan-VEGFR inhibitor
Product Description: AMG-706 (Motesanib) is an orally-available, nicotinamide-based, ATP-competitive inhibitor of the VEGFR family of kinases, KIT, and PDGFR with IC50s of 2, 3, and 6 nM, 8 nM, and 84 nM (for VEGFR1, VEGFR2, and VEGFR3), respectively. Besides Ret activity (IWeb Site click
Chemical Formula: C22H23N5O.2H3PO4
Molecular Weight: 569.44
‘&“CAS NO: 129453-61-8 Fulvestrant
Purity: 98%
Appearance: White
Chemical Name: 3-Pyridinecarboxamide, N-(2,3-dihydro-3,3-dimethyl-1H-indol-6-yl)-2-[(4-pyridinylmethyl)amino]-Epigenetics inhibitors
Solubility: Up to 100mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/7623609
