Product Name: AG-014699 (PF-01367338, Rucaparib) | PARP1/2 inhibitor
Product Description: AG-014699 (Rucaparib) is an intraveneously-administered, azepinone-indole-based inhibitor of PARP 1 and 2 (Ki = 1.4 nM) [1] AG-014699 induces selective cytotoxicity in tumor cells defective in homologous recombination repair (HRR) through BRCA1 and 2 mutaMedchemexpress.com
Chemical Formula: C19H18FN3O.H3PO4
Molecular Weight: 421.36
‘&“CAS NO: 915363-56-3 Cot inhibitor-2
Purity: 98%
Appearance: Yellow
Chemical Name: 8-Fluoro-2-(4-methylaminomethyl-phenyl)-1,3,4,5-tetrahydro-azepino[5,4,3-cd]indol-6-one phosphateInflammation/Immunology inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24099996
