Product Name: A83-01 | ALK4/5/7 inhibitor
Product Description: A83-01 is a selective inhibitor of ALK5 (12nM), ALK4 (45nM), and ALK7 (7.5 nM), and only weakly inhibits ALK1, 2, 3, and 6. It inhibits the TGF-β-induced epithelial-to-mesenchymal transition (EMT) via the inhibition of Smad2 phosphorylation. A83-01 hMedchemexpress
Chemical Formula: C25H19N5S
Molecular Weight: 421.52
‘&“CAS NO: 1627503-67-6 LDN-214117
Purity: 98%
Appearance: Pale yellow solid
Chemical Name: 3-(6-methylpyridin-2-yl)-N-phenyl-4-(quinolin-4-yl)-1H-pyrazole-1-carbothioamideThrombin inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/15908606
